Ketamine: The Future of Depression Treatment?

Treatment then consists of six infusions over 12 days. Each infusion lasts about 45 minutes. Side effects, which often include confusion, lucid daydreaming, and fuzzy vision, clear up quickly. Patients are watched closely and must have pre-arranged transport home. They’re barred from driving or using heavy machinery for 24 hours.

Abreu says in his experience, the side effects “go away as soon as the infusion is over, and patients don’t have hallucinations.”

Abreu says about three quarters of his patients aged 15 to 55 benefit from ketamine. Older patients have a lower response rate. The initial six infusions cost $3,800, the beneficial effects of which last anywhere from 3 to 5 weeks for some patients, and up to 12 weeks for others. Patients return as needed for single boosters, which cost $600. Because the FDA has not approved ketamine for this use, insurance doesn’t cover it.

A Stanford researcher is pioneering a dramatic shift in how we treat depression — and you can try her new tool right now

“A premise of CBT is it’s not the things that happen to us — it’s how we react to them,” Darcy said.

.. Woebot uses that methodology to point out areas where a person might be engaging in what’s called negative self-talk, which can mean they see the environment around them in a distorted way and feel bad about it.

.. For example, if a friend forgot about your birthday, you might tell Woebot something like, “No one ever remembers me,” or “I don’t have any real friends.” Woebot might respond by saying you’re engaging in a type of negative self-talk called all-or-nothing thinking, which is a distortion of reality. In reality, you do have friends, and people doremember you. One of those friends simply forgot your birthday.



Mark Beeman: Northwestern University: Creative Brain Lab

Research Interests

I want to know how people think. I am particularly interested in “high-level cognition,” such as how people understand whole stories, and solve complex problems. I particularly want to know how the brain thinks. All research on the brain and on thinking or perceiving, without regard to the brain, is interesting and useful. But I find it particularly satisfying to try to link the brain’s wetware to the mind’s software. Not just for the sake of connecting the mental realm to the physical, but because evidence from each domain helps constrain theories in the other, hopefully providing novel insights into both. Which brings me to my research…